BAR+ is a server for the annotation of protein sequences relying on
a comparative large-scale genome analysis across 988 species and the entire UniProt. With BAR+
and a sequence/set of sequences (maximum number per run=50) you can annotate when possible:
function (Gene Ontology), structure and ligands (Protein Data Bank), structural classification
(SCOP), protein domains (Pfam). Also if your sequence falls into a cluster with a
structural/some structural template/s we provide an alignment towards the template/templates
based on the Cluster-HMM (HMM profile) that allows you to directly compute your 3D model.
Cluster HMMs (over 10.000) are available for downloading.
(*)
Sequence already clustered in BAR+
Sequence that falls in clusters with Sequence Identity ≥ 40% and Coverage ≥ 90% (validated annotation)
Sequence that falls in clusters with Sequence Identity < 40% and Coverege < 90% (not-validated annotation)
Sequence already clustered in BAR+
Sequence that falls in clusters with Sequence Identity ≥ 40% and Coverage ≥ 90% (validated annotation)
Sequence that falls in clusters with Sequence Identity < 40% and Coverege < 90% (not-validated annotation)