Input box
The server can take one of the following inputs:
- UniProtKB accession
- EnsEMBL accession
- GO Term
- Pfam term
- Gene name
- Organism (i.e. Homo sapiens)
- Taxonomy (i.e. canis)
- PDB
You can choose the appropriate search using the drop-down menu on the right of the search field.
Output
The output is provided in a table that contains the following information:
on the first page, you get a list of sequences matching your search criteria. For each sequences you can see:
- the list of UniProtKB accession
- the list of Ensembl accession
- the cluster-id of the sequence
- the length of the sequence
Clicking on the UniProtKB accession opens the uniprot.org page about the specific identifier.
The link on the cluster number opens a new output containing the following information:
- Some markers near the heading:
when present, the cluster contains protein sequences with experimentally validated GO terms. Each statistically validated annotation with experimental evidence code is also marked with the same symbol
when present, the cluster contains annotations from the SwissProt database
when present, the cluster contains statistically validated annotations
- a list of PDB from the cluster, each with coverage and a link to the HMM alignment with the sequence
- a list of statistically validated Pfam domains, each with its associated description and P-value
- a list of statistically validated GO Terms, each with its associated description and P-value. Terms are sorted from the deepest in the ontology to the more general.
- Terms marked with
also have an experimental evidence code (EXP, IDA, IPI, IMP, IGI and IEP)
- Terms marked with U are directly associated or ancestors of terms associated to the query sequence in UniprotKB or Ensembl
- Terms marked with
- a list of not statistically validated Pfam domains, each with its associated description
- a list of not statistically validated GO Terms, each with its associated description